Oncolytic potency of HER-2 retargeted VSV-FH hybrid viruses: the role of receptor ligand affinity

The hybrid oncolytic vesicular stomatitis virus (VSV-FH) deleted for its G glycoprotein and displaying the measles virus (MV) envelope glycoproteins (hemagglutinin H and fusion F) is fusogenic, infects cells via any of the three MV receptors and has potent oncolytic activity against subcutaneous and...

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Bibliographic Details
Published in:Mol Ther Oncolytics
Main Authors: Ayala Breton, Camilo, Wikan, Nitwara, Abbuhl, Arinda, Smith, Duncan R, Russell, Stephen J, Peng, Kah-Whye
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4782949/
https://ncbi.nlm.nih.gov/pubmed/27119107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mto.2015.12
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