IL-13Rα2-Bearing, Type II NKT Cells Reactive to Sulfatide Self-Antigen Populate the Mucosa of Ulcerative Colitis

OBJECTIVE: Previous studies have shown that ulcerative colitis (UC) is associated with the presence of lamina propria non-invariant (Type II) NKT cells producing IL-13 and mediating epithelial cell cytotoxicity. Here we sought to define the antigen(s) stimulating the NKT cells and to quantitate thes...

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Bibliografiske detaljer
Udgivet i:Gut
Main Authors: Fuss, Ivan J., Joshi, Bharat, Yang, Zhiqiong, Degheidy, Heba, Fichtner-Feigl, Stefan, de Souza, Heitor, Rieder, Florian, Scaldaferri, Franco, Schirbel, Anja, Scarpa, Melania, West, Gail, Yi, Chuli, Xu, Lili, Leland, Pamela, Yao, Michael, Mannon, Peter, Puri, Raj K., Fiocchi, Claudio, Strober, Warren
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4782805/
https://ncbi.nlm.nih.gov/pubmed/24515806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2013-305671
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