Inflammatory Phenotype of Intrahepatic Sulfatide-Reactive Type II NKT Cells in Humans With Autoimmune Hepatitis

Background: Natural Killer T (NKT) cells are CD1d-restricted innate-like T cells that can rapidly release stored cytokines upon recognition of lipid antigens. In mice, type I NKT cells seem to promote liver inflammation, whereas type II NKT cells seem to restrict hepatitis. Here, we aimed at charact...

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Vydáno v:Front Immunol
Hlavní autoři: Sebode, Marcial, Wigger, Jennifer, Filpe, Pamela, Fischer, Lutz, Weidemann, Sören, Krech, Till, Weiler-Normann, Christina, Peiseler, Moritz, Hartl, Johannes, Tolosa, Eva, Herkel, Johannes, Schramm, Christoph, Lohse, Ansgar W., Arrenberg, Philomena
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6546815/
https://ncbi.nlm.nih.gov/pubmed/31191516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01065
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