Nonclassical CD1d-restricted NK T cells that produce IL-13 characterize an atypical Th2 response in ulcerative colitis

While Crohn disease (CD) has been clearly identified as a Th1 inflammation, the immunopathogenesis of its counterpart inflammatory bowel disease, ulcerative colitis (UC), remains enigmatic. Here we show that lamina propria T (LPT) cells from UC patients produce significantly greater amounts of IL-13...

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Autori principali: Fuss, Ivan J., Heller, Frank, Boirivant, Monica, Leon, Francisco, Yoshida, Masaru, Fichtner-Feigl, Stefan, Yang, Zhiqiong, Exley, Mark, Kitani, Atsushi, Blumberg, Richard S., Mannon, Peter, Strober, Warren
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2004
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC406524/
https://ncbi.nlm.nih.gov/pubmed/15146247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200419836
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