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A spatial model predicts that dispersal and cell turnover limit intratumour heterogeneity
Most cancers in humans are large, measuring centimetres in diameter, and composed of many billions of cells(1). An equivalent mass of normal cells would be highly heterogeneous as a result of the mutations that occur during each cell division. What is remarkable about cancers is that virtually every...
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| Published in: | Nature |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4782800/ https://ncbi.nlm.nih.gov/pubmed/26308893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14971 |
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