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Generation of functionally active HIV-1 specific CD8(+) CTL in intestinal mucosa following mucosal, systemic or mixed prime-boost immunization
Gastrointestinal and vaginal mucosa are major sites of entry in natural HIV infection and therefore the preferred sites to elicit high-avidity CD8(+) CTL by vaccination. We directly compare systemic and mucosal immunization in mice after DNA priming and boosting with rgp160 env expressed either in M...
Shranjeno v:
| izdano v: | Virology |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4782776/ https://ncbi.nlm.nih.gov/pubmed/18793787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.08.019 |
| Oznake: |
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