Imaging the accumulation and suppression of tau pathology using multiparametric MRI

Mouse models of Alzheimer's disease have served as valuable tools for investigating pathogenic mechanisms relating to neurodegeneration, including tau-mediated and neurofibrillary tangle pathology—a major hallmark of the disease. In this work, we have used multiparametric magnetic resonance ima...

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Detalhes bibliográficos
Publicado no:Neurobiol Aging
Main Authors: Holmes, Holly E., Colgan, Niall, Ismail, Ozama, Ma, Da, Powell, Nick M., O'Callaghan, James M., Harrison, Ian F., Johnson, Ross A., Murray, Tracey K., Ahmed, Zeshan, Heggenes, Morton, Fisher, Alice, Cardoso, M.J., Modat, Marc, Walker-Samuel, Simon, Fisher, Elizabeth M.C., Ourselin, Sebastien, O'Neill, Michael J., Wells, Jack A., Collins, Emily C., Lythgoe, Mark F.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4782737/
https://ncbi.nlm.nih.gov/pubmed/26923415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2015.12.001
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