Increased cerebral vascular reactivity in the tau expressing rTg4510 mouse: evidence against the role of tau pathology to impair vascular health in Alzheimer's disease

Vascular abnormalities are a key feature of Alzheimer's disease (AD). Imaging of cerebral vascular reactivity (CVR) is a powerful tool to investigate vascular health in clinical populations although the cause of reduced CVR in AD patients is not fully understood. We investigated the specific ro...

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Vydáno v:J Cereb Blood Flow Metab
Hlavní autoři: Wells, Jack A, Holmes, Holly E, O'Callaghan, James M, Colgan, Niall, Ismail, Ozama, Fisher, Elizabeth MC, Siow, Bernard, Murray, Tracey K, Schwarz, Adam J, O'Neill, Michael J, Collins, Emily C, Lythgoe, Mark F
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
Témata:
Brief Communication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348392/
https://ncbi.nlm.nih.gov/pubmed/25515210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.224
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