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Increased cerebral vascular reactivity in the tau expressing rTg4510 mouse: evidence against the role of tau pathology to impair vascular health in Alzheimer's disease

Vascular abnormalities are a key feature of Alzheimer's disease (AD). Imaging of cerebral vascular reactivity (CVR) is a powerful tool to investigate vascular health in clinical populations although the cause of reduced CVR in AD patients is not fully understood. We investigated the specific ro...

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Detalles Bibliográficos
Publicado en:J Cereb Blood Flow Metab
Main Authors: Wells, Jack A, Holmes, Holly E, O'Callaghan, James M, Colgan, Niall, Ismail, Ozama, Fisher, Elizabeth MC, Siow, Bernard, Murray, Tracey K, Schwarz, Adam J, O'Neill, Michael J, Collins, Emily C, Lythgoe, Mark F
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348392/
https://ncbi.nlm.nih.gov/pubmed/25515210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.224
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