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Imaging the accumulation and suppression of tau pathology using multiparametric MRI

Mouse models of Alzheimer's disease have served as valuable tools for investigating pathogenic mechanisms relating to neurodegeneration, including tau-mediated and neurofibrillary tangle pathology—a major hallmark of the disease. In this work, we have used multiparametric magnetic resonance ima...

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Dades bibliogràfiques
Publicat a:Neurobiol Aging
Autors principals: Holmes, Holly E., Colgan, Niall, Ismail, Ozama, Ma, Da, Powell, Nick M., O'Callaghan, James M., Harrison, Ian F., Johnson, Ross A., Murray, Tracey K., Ahmed, Zeshan, Heggenes, Morton, Fisher, Alice, Cardoso, M.J., Modat, Marc, Walker-Samuel, Simon, Fisher, Elizabeth M.C., Ourselin, Sebastien, O'Neill, Michael J., Wells, Jack A., Collins, Emily C., Lythgoe, Mark F.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4782737/
https://ncbi.nlm.nih.gov/pubmed/26923415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2015.12.001
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