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Therapeutic interactions of autophagy with radiation and temozolomide in glioblastoma: evidence and issues to resolve

Glioblastoma is a unique model of non-metastasising disease that kills the vast majority of patients through local growth, despite surgery and local irradiation. Glioblastoma cells are resistant to apoptotic stimuli, and their death occurs through autophagy. This review aims to critically present ou...

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Bibliografiske detaljer
Udgivet i:Br J Cancer
Main Authors: Koukourakis, Michael I, Mitrakas, Achilleas G, Giatromanolaki, Alexandra
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4782209/
https://ncbi.nlm.nih.gov/pubmed/26889975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.19
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