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Therapeutic interactions of autophagy with radiation and temozolomide in glioblastoma: evidence and issues to resolve

Glioblastoma is a unique model of non-metastasising disease that kills the vast majority of patients through local growth, despite surgery and local irradiation. Glioblastoma cells are resistant to apoptotic stimuli, and their death occurs through autophagy. This review aims to critically present ou...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Koukourakis, Michael I, Mitrakas, Achilleas G, Giatromanolaki, Alexandra
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4782209/
https://ncbi.nlm.nih.gov/pubmed/26889975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.19
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