Arpin downregulation in breast cancer is associated with poor prognosis

BACKGROUND: The Arp2/3 complex is required for cell migration and invasion. The Arp2/3 complex and its activators, such as the WAVE complex, are deregulated in diverse cancers. Here we investigate the expression of Arpin, the Arp2/3 inhibitory protein that antagonises the WAVE complex. METHODS: We u...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Lomakina, Maria E, Lallemand, François, Vacher, Sophie, Molinie, Nicolas, Dang, Irene, Cacheux, Wulfran, Chipysheva, Tamara A, Ermilova, Valeria D, de Koning, Leanne, Dubois, Thierry, Bièche, Ivan, Alexandrova, Antonina Y, Gautreau, Alexis
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4782208/
https://ncbi.nlm.nih.gov/pubmed/26867158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.18
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