Arpin downregulation in breast cancer is associated with poor prognosis

BACKGROUND: The Arp2/3 complex is required for cell migration and invasion. The Arp2/3 complex and its activators, such as the WAVE complex, are deregulated in diverse cancers. Here we investigate the expression of Arpin, the Arp2/3 inhibitory protein that antagonises the WAVE complex. METHODS: We u...

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Detalles Bibliográficos
Publicado en:Br J Cancer
Autores principales: Lomakina, Maria E, Lallemand, François, Vacher, Sophie, Molinie, Nicolas, Dang, Irene, Cacheux, Wulfran, Chipysheva, Tamara A, Ermilova, Valeria D, de Koning, Leanne, Dubois, Thierry, Bièche, Ivan, Alexandrova, Antonina Y, Gautreau, Alexis
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2016
Materias:
Molecular Diagnostics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4782208/
https://ncbi.nlm.nih.gov/pubmed/26867158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.18
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