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The Arp2/3 inhibitory protein Arpin is dispensable for chemotaxis

Arpin is an Arp2/3 inhibitory protein, which decreases the protrusion lifetime and hence directional persistence in the migration of diverse cells. Arpin is activated by the small GTPase Rac, which controls cell protrusion, thus closing a negative feedback loop that renders the protrusion intrinsica...

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Détails bibliographiques
Publié dans:Biol Cell
Auteurs principaux: Dang, Irène, Linkner, Joern, Yan, Jun, Irimia, Daniel, Faix, Jan, Gautreau, Alexis
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5506374/
https://ncbi.nlm.nih.gov/pubmed/28186323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/boc.201600064
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