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The Arp2/3 inhibitory protein Arpin is dispensable for chemotaxis

Arpin is an Arp2/3 inhibitory protein, which decreases the protrusion lifetime and hence directional persistence in the migration of diverse cells. Arpin is activated by the small GTPase Rac, which controls cell protrusion, thus closing a negative feedback loop that renders the protrusion intrinsica...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biol Cell
Main Authors: Dang, Irène, Linkner, Joern, Yan, Jun, Irimia, Daniel, Faix, Jan, Gautreau, Alexis
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5506374/
https://ncbi.nlm.nih.gov/pubmed/28186323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/boc.201600064
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