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Coupling pre-mRNA splicing and 3′ end formation to mRNA export: alternative ways to punch the nuclear export clock

How does a mammalian cell determine when newly synthesized mRNAs are fully processed and appropriate for nuclear export? Müller-McNicoll and colleagues (pp. 553–566) expand on mechanisms known to be mediated by nuclear export factor 1 (NXF1) by describing SR proteins as NXF1 adaptors that flag alter...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Elbarbary, Reyad A., Maquat, Lynne E.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4782043/
https://ncbi.nlm.nih.gov/pubmed/26944675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.278937.116
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