Tal, a Tsg101-specific E3 ubiquitin ligase, regulates receptor endocytosis and retrovirus budding

The tumor suppressor gene 101 (tsg101) regulates vesicular trafficking processes in yeast and mammals. We report a novel protein, Tal (Tsg101-associated ligase), whose RING finger is necessary for multiple monoubiquitylation of Tsg101. Bivalent binding of Tsg101 to a tandem tetrapeptide motif (PTAP)...

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Bibliografiska uppgifter
Huvudupphovsmän: Amit, Ido, Yakir, Liat, Katz, Menachem, Zwang, Yaara, Marmor, Mina D., Citri, Ami, Shtiegman, Keren, Alroy, Iris, Tuvia, Shmuel, Reiss, Yuval, Roubini, Eli, Cohen, Maya, Wides, Ron, Bacharach, Eran, Schubert, Ullrich, Yarden, Yosef
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 2004
Ämnen:
Research Papers
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC478194/
https://ncbi.nlm.nih.gov/pubmed/15256501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.294904
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