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Unraveling Entropic Rate Acceleration Induced by Solvent Dynamics in Membrane Enzymes

Enzyme catalysis evolved in an aqueous environment. The influence of solvent dynamics on catalysis is, however, currently poorly understood and usually neglected. The study of water dynamics in enzymes and the associated thermodynamical consequences is highly complex and has involved computer simula...

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Bibliografski detalji
Izdano u:J Vis Exp
Glavni autori: Kürten, Charlotte, Syrén, Per-Olof
Format: Artigo
Jezik:Inglês
Izdano: MyJove Corporation 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4781653/
https://ncbi.nlm.nih.gov/pubmed/26862836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/53168
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