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Unraveling Entropic Rate Acceleration Induced by Solvent Dynamics in Membrane Enzymes

Enzyme catalysis evolved in an aqueous environment. The influence of solvent dynamics on catalysis is, however, currently poorly understood and usually neglected. The study of water dynamics in enzymes and the associated thermodynamical consequences is highly complex and has involved computer simula...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Kürten, Charlotte, Syrén, Per-Olof
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4781653/
https://ncbi.nlm.nih.gov/pubmed/26862836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/53168
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