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Unraveling Entropic Rate Acceleration Induced by Solvent Dynamics in Membrane Enzymes

Enzyme catalysis evolved in an aqueous environment. The influence of solvent dynamics on catalysis is, however, currently poorly understood and usually neglected. The study of water dynamics in enzymes and the associated thermodynamical consequences is highly complex and has involved computer simula...

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Dettagli Bibliografici
Pubblicato in:J Vis Exp
Autori principali: Kürten, Charlotte, Syrén, Per-Olof
Natura: Artigo
Lingua:Inglês
Pubblicazione: MyJove Corporation 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4781653/
https://ncbi.nlm.nih.gov/pubmed/26862836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/53168
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