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Assessing methods to specify the target difference for a randomised controlled trial: DELTA (Difference ELicitation in TriAls) review.

BACKGROUND: The randomised controlled trial (RCT) is widely considered to be the gold standard study for comparing the effectiveness of health interventions. Central to the design and validity of a RCT is a calculation of the number of participants needed (the sample size). The value used to determi...

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Bibliographische Detailangaben
Veröffentlicht in:Health Technol Assess
Hauptverfasser: Cook, Jonathan A, Hislop, Jennifer, Adewuyi, Temitope E, Harrild, Kirsten, Altman, Douglas G, Ramsay, Craig R, Fraser, Cynthia, Buckley, Brian, Fayers, Peter, Harvey, Ian, Briggs, Andrew H, Norrie, John D, Fergusson, Dean, Ford, Ian, Vale, Luke D
Format: Artigo
Sprache:Inglês
Veröffentlicht: NIHR Journals Library 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4781097/
https://ncbi.nlm.nih.gov/pubmed/24806703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3310/hta18280
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