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Assessing methods to specify the target difference for a randomised controlled trial: DELTA (Difference ELicitation in TriAls) review.

BACKGROUND: The randomised controlled trial (RCT) is widely considered to be the gold standard study for comparing the effectiveness of health interventions. Central to the design and validity of a RCT is a calculation of the number of participants needed (the sample size). The value used to determi...

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Publicado en:Health Technol Assess
Main Authors: Cook, Jonathan A, Hislop, Jennifer, Adewuyi, Temitope E, Harrild, Kirsten, Altman, Douglas G, Ramsay, Craig R, Fraser, Cynthia, Buckley, Brian, Fayers, Peter, Harvey, Ian, Briggs, Andrew H, Norrie, John D, Fergusson, Dean, Ford, Ian, Vale, Luke D
Formato: Artigo
Idioma:Inglês
Publicado: NIHR Journals Library 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4781097/
https://ncbi.nlm.nih.gov/pubmed/24806703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3310/hta18280
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