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Choosing the target difference (‘effect size’) for a randomised controlled trial - DELTA(2) guidance protocol
BACKGROUND: A key step in the design of a randomised controlled trial (RCT) is the estimation of the number of participants needed. By far the most common approach is to specify a target difference and then estimate the corresponding sample size; this sample size is chosen to provide reassurance tha...
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| Published in: | Trials |
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| Main Authors: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5469157/ https://ncbi.nlm.nih.gov/pubmed/28606102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-017-1969-5 |
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