Choosing the target difference (‘effect size’) for a randomised controlled trial - DELTA(2) guidance protocol

BACKGROUND: A key step in the design of a randomised controlled trial (RCT) is the estimation of the number of participants needed. By far the most common approach is to specify a target difference and then estimate the corresponding sample size; this sample size is chosen to provide reassurance tha...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Trials
Autori principali: Cook, Jonathan A., Julious, Steven A., Sones, William, Rothwell, Joanne C., Ramsay, Craig R., Hampson, Lisa V., Emsley, Richard, Walters, Stephen J., Hewitt, Catherine, Bland, Martin, Fergusson, Dean A., Berlin, Jesse A., Altman, Doug, Vale, Luke D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
Soggetti:
Study Protocol
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5469157/
https://ncbi.nlm.nih.gov/pubmed/28606102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-017-1969-5
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