Choosing the target difference (‘effect size’) for a randomised controlled trial - DELTA(2) guidance protocol

BACKGROUND: A key step in the design of a randomised controlled trial (RCT) is the estimation of the number of participants needed. By far the most common approach is to specify a target difference and then estimate the corresponding sample size; this sample size is chosen to provide reassurance tha...

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Detalhes bibliográficos
Publicado no:Trials
Main Authors: Cook, Jonathan A., Julious, Steven A., Sones, William, Rothwell, Joanne C., Ramsay, Craig R., Hampson, Lisa V., Emsley, Richard, Walters, Stephen J., Hewitt, Catherine, Bland, Martin, Fergusson, Dean A., Berlin, Jesse A., Altman, Doug, Vale, Luke D.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Study Protocol
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5469157/
https://ncbi.nlm.nih.gov/pubmed/28606102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-017-1969-5
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