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VDJ-Seq: Deep Sequencing Analysis of Rearranged Immunoglobulin Heavy Chain Gene to Reveal Clonal Evolution Patterns of B Cell Lymphoma

Understanding tumor clonality is critical to understanding the mechanisms involved in tumorigenesis and disease progression. In addition, understanding the clonal composition changes that occur within a tumor in response to certain micro-environment or treatments may lead to the design of more sophi...

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Detalles Bibliográficos
Publicado en:J Vis Exp
Main Authors: Jiang, Yanwen, Nie, Kui, Redmond, David, Melnick, Ari M., Tam, Wayne, Elemento, Olivier
Formato: Artigo
Idioma:Inglês
Publicado: MyJove Corporation 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4780861/
https://ncbi.nlm.nih.gov/pubmed/26780364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/53215
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