Deep sequencing reveals clonal evolution patterns and mutation events associated with relapse in B-cell lymphomas

BACKGROUND: Molecular mechanisms associated with frequent relapse of diffuse large B-cell lymphoma (DLBCL) are poorly defined. It is especially unclear how primary tumor clonal heterogeneity contributes to relapse. Here, we explore unique features of B-cell lymphomas - VDJ recombination and somatic...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Jiang, Yanwen, Redmond, David, Nie, Kui, Eng, Ken W, Clozel, Thomas, Martin, Peter, Tan, Leonard HC, Melnick, Ari M, Tam, Wayne, Elemento, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158101/
https://ncbi.nlm.nih.gov/pubmed/25123191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0432-0
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados