A New Nanobody-Based Biosensor to Study Endogenous PARP1 In Vitro and in Live Human Cells

Poly(ADP-ribose) polymerase 1 (PARP1) is a key player in DNA repair, genomic stability and cell survival and it emerges as a highly relevant target for cancer therapies. To deepen our understanding of PARP biology and mechanisms of action of PARP1-targeting anti-cancer compounds, we generated a nove...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Buchfellner, Andrea, Yurlova, Larisa, Nüske, Stefan, Scholz, Armin M., Bogner, Jacqueline, Ruf, Benjamin, Zolghadr, Kourosh, Drexler, Sophie E., Drexler, Guido A., Girst, Stefanie, Greubel, Christoph, Reindl, Judith, Siebenwirth, Christian, Romer, Tina, Friedl, Anna A., Rothbauer, Ulrich
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2016
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4780744/
https://ncbi.nlm.nih.gov/pubmed/26950694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151041
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia