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Enzyme catalysis by entropy without Circe effect

Entropic effects have often been invoked to explain the extraordinary catalytic power of enzymes. In particular, the hypothesis that enzymes can use part of the substrate-binding free energy to reduce the entropic penalty associated with the subsequent chemical transformation has been very influenti...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Kazemi, Masoud, Himo, Fahmi, Åqvist, Johan
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4780625/
https://ncbi.nlm.nih.gov/pubmed/26755610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1521020113
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