Early BAFF receptor blockade mitigates murine Sjögren's syndrome: Concomitant targeting of CXCL13 and the BAFF receptor prevents salivary hypofunction

Sjögren's Syndrome (SS) is a debilitating autoimmune disease. Patients with SS may develop xerostomia. This process is progressive, and there are no therapeutics that target disease etiology. We hypothesized BAFF receptor (BAFFR) blockade would mitigate SS disease development, and neutralizatio...

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Foilsithe in:Clin Immunol
Main Authors: Sharma, Arjun, Kiripolsky, Jeremy, Klimatcheva, Ekaterina, Howell, Alan, Fereidouni, Farzad, Levenson, Richard, Rothstein, Thomas L., Kramer, Jill M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4780410/
https://ncbi.nlm.nih.gov/pubmed/26826598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2016.01.015
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