Lymphotoxin-beta receptor blockade reduces CXCL13 in lacrimal glands and improves corneal integrity in the NOD model of Sjögren's syndrome

INTRODUCTION: In Sjögren's syndrome, keratoconjunctivitis sicca (dry eye) is associated with infiltration of lacrimal glands by leukocytes and consequent losses of tear-fluid production and the integrity of the ocular surface. We investigated the effect of blockade of the lymphotoxin-beta recep...

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Bibliografiska uppgifter
Huvudupphovsmän: Fava, Roy A, Kennedy, Susan M, Wood, Sheryl G, Bolstad, Anne I, Bienkowska, Jadwiga, Papandile, Adrian, Kelly, John A, Mavragani, Clio P, Gatumu, Margaret, Skarstein, Kathrine, Browning, Jeffrey L
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2011
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334628/
https://ncbi.nlm.nih.gov/pubmed/22044682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3507
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