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Insulin Resistance in Human iPS Cells Reduces Mitochondrial Size and Function
Insulin resistance, a critical component of type 2 diabetes (T2D), precedes and predicts T2D onset. T2D is also associated with mitochondrial dysfunction. To define the cause-effect relationship between insulin resistance and mitochondrial dysfunction, we compared mitochondrial metabolism in induced...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4780029/ https://ncbi.nlm.nih.gov/pubmed/26948272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22788 |
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