Severe Insulin Resistance Alters Metabolism in Mesenchymal Progenitor Cells

Donohue syndrome (DS) is characterized by severe insulin resistance due to mutations in the insulin receptor (INSR) gene. To identify molecular defects contributing to metabolic dysregulation in DS in the undifferentiated state, we generated mesenchymal progenitor cells (MPCs) from induced pluripote...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Endocrinology
Päätekijät: Balhara, Bharti, Burkart, Alison, Topcu, Vehap, Lee, Youn-Kyoung, Cowan, Chad, Kahn, C. Ronald, Patti, Mary-Elizabeth
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Endocrine Society 2015
Aiheet:
Original Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4430624/
https://ncbi.nlm.nih.gov/pubmed/25811318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1403
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia