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A novel vaccination strategy mediating the induction of lung-resident memory CD8 T cells confers heterosubtypic immunity against future pandemic influenza virus

The currently used vaccine strategy to combat influenza A virus (IAV) aims to provide highly specific immunity to circulating seasonal IAV strains. However, the outbreak of 2009 influenza pandemic highlights the danger in this strategy. Here, we tested the hypothesis that universal vaccination that...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Immunol
Hauptverfasser: Lee, Yu-Na, Lee, Young-Tae, Kim, Min-Chul, Gewirtz, Andrew T., Kang, Sang-Moo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779729/
https://ncbi.nlm.nih.gov/pubmed/26864033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501637
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