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Repeated Antigen Exposure Extends the Durability of Influenza-Specific Lung-Resident Memory CD8(+) T Cells and Heterosubtypic Immunity
Lung-resident primary memory CD8(+) T cell populations (T(rm)) induced by a single influenza infection decline within months, rendering the host susceptible to new heterosubtypic influenza infections. Here, we demonstrate that, relative to single virus exposure, repeated antigen exposure dramaticall...
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| Gepubliceerd in: | Cell Rep |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6258017/ https://ncbi.nlm.nih.gov/pubmed/30257199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.08.073 |
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