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Repeated Antigen Exposure Extends the Durability of Influenza-Specific Lung-Resident Memory CD8(+) T Cells and Heterosubtypic Immunity
Lung-resident primary memory CD8(+) T cell populations (T(rm)) induced by a single influenza infection decline within months, rendering the host susceptible to new heterosubtypic influenza infections. Here, we demonstrate that, relative to single virus exposure, repeated antigen exposure dramaticall...
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| 出版年: | Cell Rep |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6258017/ https://ncbi.nlm.nih.gov/pubmed/30257199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.08.073 |
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