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Enhanced clonal burst size corrects an otherwise defective memory response by CD8(+) recent thymic emigrants

The youngest peripheral T cells (recent thymic emigrants or RTEs) are functionally distinct from naïve T cells that have completed post-thymic maturation. We now assess the RTE memory response, and find that RTEs produced less granzyme B than their mature counterparts during infection, but prolifera...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Deets, Katherine A., Berkley, Amy M., Bergsbaken, Tessa, Fink, Pamela J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779721/
https://ncbi.nlm.nih.gov/pubmed/26873989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502525
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