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GAPDH Binding to TNF-α mRNA Contributes to Post-Transcriptional Repression in Monocytes: A Novel Mechanism of Communication between Inflammation and Metabolism
Expression of the inflammatory cytokine TNF is tightly controlled. During endotoxin tolerance, transcription of TNF mRNA is repressed, although not entirely eliminated. Production of TNF cytokine, however, is further controlled by post-transcriptional regulation. In this study, we detail a mechanism...
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| Publicado en: | J Immunol |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4779706/ https://ncbi.nlm.nih.gov/pubmed/26843329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501345 |
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