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GAPDH Binding to TNF-α mRNA Contributes to Post-Transcriptional Repression in Monocytes: A Novel Mechanism of Communication between Inflammation and Metabolism

Expression of the inflammatory cytokine TNF is tightly controlled. During endotoxin tolerance, transcription of TNF mRNA is repressed, although not entirely eliminated. Production of TNF cytokine, however, is further controlled by post-transcriptional regulation. In this study, we detail a mechanism...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Immunol
Päätekijät: Millet, Patrick, Vachharajani, Vidula, McPhail, Linda, Yoza, Barbara, McCall, Charles
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779706/
https://ncbi.nlm.nih.gov/pubmed/26843329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501345
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