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A long journey coming to fruition: In sight of the pre-selection T-cell repertoire
In addition to MHC restriction and its structural correlate, the recognition of an MHC-peptide complex by the T-cell antigen receptor (TCR), T-cell reactivity is constrained by positive and negative selection in the thymus. While mouse genetic studies have provided compelling evidence for both proce...
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| Veröffentlicht in: | Eur J Immunol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4779685/ https://ncbi.nlm.nih.gov/pubmed/26846172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201646292 |
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