Characterization of Folic Acid and Poly(amidoamine) Dendrimer Interactions with Folate Binding Protein: A Force-Pulling Study

Atomic force microscopy force-pulling experiments have been used to measure the binding forces between folic acid (FA) conjugated poly(amidoamine) (PAMAM) dendrimers and folate binding protein (FBP). The generation 5 (G5) PAMAM conjugates contained an average of 2.7, 4.7, and 7.2 FA per dendrimer. T...

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Bibliografiske detaljer
Udgivet i:J Phys Chem B
Main Authors: Leroueil, Pascale R., DiMaggio, Stassi, Leistra, Abigail N., Blanchette, Craig D., Orme, Christine, Sinniah, Kumar, Orr, Bradford G., Holl, Mark M. Banaszak
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779365/
https://ncbi.nlm.nih.gov/pubmed/26256755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.5b05391
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