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Poly(amidoamine) Dendrimers on Lipid Bilayers I: Free Energy and Conformation of Binding

Third-generation (G3) poly(amidoamine) (PAMAM) dendrimers are simulated approaching 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) bilayers with fully atomistic molecular dynamics, which enables the calculation of a free energy profile along the approach coordinate. Three different dendrimer ter...

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Main Authors: Kelly, Christopher V., Leroueil, Pascale R., Nett, Elizabeth K., Wereszczynski, Jeffery M., Baker, James R., Orr, Bradford G., Holl, Mark M. Banaszak, Andricioaei, Ioan
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925445/
https://ncbi.nlm.nih.gov/pubmed/18620450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp801377a
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