Whole-Exome Sequencing Reveals Mutations in Genes Linked to Hemophagocytic Lymphohistiocytosis and Macrophage Activation Syndrome in Fatal Cases of H1N1 Influenza

Background. Severe H1N1 influenza can be lethal in otherwise healthy individuals and can have features of reactive hemophagocytic lymphohistiocytosis (HLH). HLH is associated with mutations in lymphocyte cytolytic pathway genes, which have not been previously explored in H1N1 influenza. Methods. Six...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Schulert, Grant S., Zhang, Mingce, Fall, Ndate, Husami, Ammar, Kissell, Diane, Hanosh, Andrew, Zhang, Kejian, Davis, Kristina, Jentzen, Jeffrey M., Napolitano, Lena, Siddiqui, Javed, Smith, Lauren B., Harms, Paul W., Grom, Alexei A., Cron, Randy Q.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779301/
https://ncbi.nlm.nih.gov/pubmed/26597256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiv550
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados