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Whole Exome Sequencing Reveals Overlap Between Macrophage Activation Syndrome in Systemic Juvenile Idiopathic Arthritis and Familial Hemophagocytic Lymphohistiocytosis

OBJECTIVE: Macrophage activation syndrome (MAS), a life-threatening complication of systemic Juvenile Idiopathic Arthritis (SJIA), resembles Familial Hemophagocytic Lymphohistiocytosis (FHLH), a constellation of autosomal recessive immune disorders resulting from deficiency in cytolytic pathway prot...

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Bibliografski detalji
Izdano u:Arthritis Rheumatol
Glavni autori: Kaufman, Kenneth M., Linghu, Bolan, Szustakowski, Joseph D., Husami, Ammar, Yang, Fan, Zhang, Kejian, Filipovich, Alexandra, Fall, Ndate, Harley, John B., Nirmala, N.R., Grom, Alexei A.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4321811/
https://ncbi.nlm.nih.gov/pubmed/25047945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38793
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