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The power of sophisticated phenotypic screening and modern mechanism-of-action methods

The enthusiasm for phenotypic screening as an approach for small-molecule discovery has increased dramatically over the last several years. The recent increase in phenotype-based discoveries is in part due to advancements in phenotypic readouts in improved disease models that recapitulate clinically...

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Detalles Bibliográficos
Publicado en:Cell Chem Biol
Main Authors: Wagner, Bridget K., Schreiber, Stuart L.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779180/
https://ncbi.nlm.nih.gov/pubmed/26933731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2015.11.008
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