Effects of Surface Composition on the Aerosolisation and Dissolution of Inhaled Antibiotic Combination Powders Consisting of Colistin and Rifampicin

Colistin is often the only effective antibiotic against the respiratory infections caused by multidrug-resistant Gram-negative bacteria. However, colistin-resistant multidrug-resistant isolates have been increasingly reported and combination therapy is preferred to combat resistance. In this study,...

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Bibliografiske detaljer
Udgivet i:AAPS J
Main Authors: Wang, Wenbo, Zhou, Qi Tony, Sun, Si-Ping, Denman, John A., Gengenbach, Thomas R., Barraud, Nicolas, Rice, Scott A., Li, Jian, Yang, Mingshi, Chan, Hak-Kim
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779103/
https://ncbi.nlm.nih.gov/pubmed/26603890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-015-9848-z
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