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Effects of Surface Composition on the Aerosolisation and Dissolution of Inhaled Antibiotic Combination Powders Consisting of Colistin and Rifampicin

Colistin is often the only effective antibiotic against the respiratory infections caused by multidrug-resistant Gram-negative bacteria. However, colistin-resistant multidrug-resistant isolates have been increasingly reported and combination therapy is preferred to combat resistance. In this study,...

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Detalhes bibliográficos
Publicado no:AAPS J
Main Authors: Wang, Wenbo, Zhou, Qi Tony, Sun, Si-Ping, Denman, John A., Gengenbach, Thomas R., Barraud, Nicolas, Rice, Scott A., Li, Jian, Yang, Mingshi, Chan, Hak-Kim
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779103/
https://ncbi.nlm.nih.gov/pubmed/26603890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-015-9848-z
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