Cerebrospinal fluid ratios with Aβ(42) predict preclinical brain β-amyloid accumulation

INTRODUCTION: Biomarkers are urgently needed for the critical yet understudied preclinical stage of Alzheimer's disease (AD). METHODS: Cerebrospinal fluid (CSF) collection, [C-11]Pittsburgh compound B (PiB) amyloid imaging, and magnetic resonance imaging were acquired in 104 cognitively healthy...

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Detalhes bibliográficos
Publicado no:Alzheimers Dement (Amst)
Main Authors: Racine, Annie M., Koscik, Rebecca L., Nicholas, Christopher R., Clark, Lindsay R., Okonkwo, Ozioma C., Oh, Jennifer M., Hillmer, Ansel T., Murali, Dhanabalan, Barnhart, Todd E., Betthauser, Tobey J., Gallagher, Catherine L., Rowley, Howard A., Dowling, N. Maritza, Asthana, Sanjay, Bendlin, Barbara B., Blennow, Kaj, Zetterberg, Henrik, Carlsson, Cynthia M., Christian, Bradley T., Johnson, Sterling C.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
CSF Biomarkers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4778249/
https://ncbi.nlm.nih.gov/pubmed/26955655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dadm.2015.11.006
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