Cerebrospinal fluid ratios with Aβ(42) predict preclinical brain β-amyloid accumulation

INTRODUCTION: Biomarkers are urgently needed for the critical yet understudied preclinical stage of Alzheimer's disease (AD). METHODS: Cerebrospinal fluid (CSF) collection, [C-11]Pittsburgh compound B (PiB) amyloid imaging, and magnetic resonance imaging were acquired in 104 cognitively healthy...

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Dades bibliogràfiques
Publicat a:Alzheimers Dement (Amst)
Autors principals: Racine, Annie M., Koscik, Rebecca L., Nicholas, Christopher R., Clark, Lindsay R., Okonkwo, Ozioma C., Oh, Jennifer M., Hillmer, Ansel T., Murali, Dhanabalan, Barnhart, Todd E., Betthauser, Tobey J., Gallagher, Catherine L., Rowley, Howard A., Dowling, N. Maritza, Asthana, Sanjay, Bendlin, Barbara B., Blennow, Kaj, Zetterberg, Henrik, Carlsson, Cynthia M., Christian, Bradley T., Johnson, Sterling C.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2015
Matèries:
CSF Biomarkers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4778249/
https://ncbi.nlm.nih.gov/pubmed/26955655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dadm.2015.11.006
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