Cerebrospinal fluid ratios with Aβ(42) predict preclinical brain β-amyloid accumulation

INTRODUCTION: Biomarkers are urgently needed for the critical yet understudied preclinical stage of Alzheimer's disease (AD). METHODS: Cerebrospinal fluid (CSF) collection, [C-11]Pittsburgh compound B (PiB) amyloid imaging, and magnetic resonance imaging were acquired in 104 cognitively healthy...

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Bibliografiske detaljer
Udgivet i:Alzheimers Dement (Amst)
Main Authors: Racine, Annie M., Koscik, Rebecca L., Nicholas, Christopher R., Clark, Lindsay R., Okonkwo, Ozioma C., Oh, Jennifer M., Hillmer, Ansel T., Murali, Dhanabalan, Barnhart, Todd E., Betthauser, Tobey J., Gallagher, Catherine L., Rowley, Howard A., Dowling, N. Maritza, Asthana, Sanjay, Bendlin, Barbara B., Blennow, Kaj, Zetterberg, Henrik, Carlsson, Cynthia M., Christian, Bradley T., Johnson, Sterling C.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2015
Fag:
CSF Biomarkers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4778249/
https://ncbi.nlm.nih.gov/pubmed/26955655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dadm.2015.11.006
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