Evaluation of the dopamine β-hydroxylase (DβH) inhibitor nepicastat in participants who meet criteria for cocaine use disorder

In the present study, we tested the hypothesis that the potent and selective dopamine-β-hydroxylase (DβH) inhibitor nepicastat would have minimal effects on cardiovascular and pharmacokinetic parameters associated with cocaine administration and would reduce the positive subjective effects produced...

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Detalhes bibliográficos
Publicado no:Prog Neuropsychopharmacol Biol Psychiatry
Main Authors: De La Garza, Richard, Bubar, Marcy J., Carbone, Crystal L., Moeller, F. Gerard, Newton, Thomas F., Anastasio, Noelle C., Harper, Tod A., Ware, David L., Fuller, Michael A., Holstein, Gaylyn J., Jayroe, Jason B., Bandak, Stephen I., Reiman, Kirsten Z., Neale, Ann C., Pickford, Lesley B., Cunningham, Kathryn A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777897/
https://ncbi.nlm.nih.gov/pubmed/25602710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pnpbp.2015.01.009
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