Catecholamine modulatory effects of nepicastat (RS-25560-197), a novel, potent and selective inhibitor of dopamine-β-hydroxylase

1. Inhibitory modulation of sympathetic nerve function may have a favourable impact on the progression of congestive heart failure. Nepicastat is a novel inhibitor of dopamine-β-hydroxylase, the enzyme which catalyses the conversion of dopamine to noradrenaline in sympathetic nerves. The in vitro ph...

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Detalhes bibliográficos
Main Authors: Stanley, William C, Li, Bin, Bonhaus, Douglas W, Johnson, Lowell G, Lee, Keiho, Porter, Seth, Walker, Keith, Martinez, Greg, Eglen, Richard M, Whiting, Roger L, Hegde, Sharath S
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564872/
https://ncbi.nlm.nih.gov/pubmed/9283721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701315
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