RS 23597-190: a potent and selective 5-HT4 receptor antagonist.

1. The pharmacological properties of RS 23597-190 (3-(piperdine-1-yl)-propyl-4-amino-5-chloro-2-methoxy benzoate hydrochloride) have been studied in vitro and in vivo. 2. RS 23597-190 competitively antagonized 5-HT4 receptor-mediated relaxations of rat, carbachol precontracted oesophageal muscularis...

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Bibliographic Details
Main Authors: Eglen, R. M., Bley, K., Bonhaus, D. W., Clark, R. D., Hegde, S. S., Johnson, L. G., Leung, E., Wong, E. H.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1993
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2176024/
https://ncbi.nlm.nih.gov/pubmed/8220871
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